Molecular Processes in Kidney Cells May ‘Prime’ Diabetics for COVID-19 Infection

Simons Foundation, October 2020

People with diabetes — especially the 20 to 40 percent with diabetic kidney disease — are among the most at risk for serious complications and death from COVID-19. A new study of gene expression utilizing machine learning peered inside the kidney cells of COVID-19 patients and diabetic kidney disease patients and made a surprising discovery: Similar molecular processes were activated in both sets of patients, revealing potential avenues of viral vulnerability. The researchers report their findings in Kidney International.